Lead Full-Stack Machine Learning & DevOps Engineer, AI/ML Prototyping & Production
Location: RemoteTeam: Therapeutics & InnovationsReports To: Director of Artificial Intelligence
About Natera
Natera is a global leader in cell-free DNA testing, revolutionizing personalized healthcare through genomics. Our Therapeutics and Innovations unit is pioneering how AI intersects with clinical applications in drug discovery, clinical development, and diagnostics.
The Opportunity
We are seeking a Senior Full-Stack ML Engineer to bridge the gap between cutting-edge AI/ML research and real-world clinical impact. This role is ideal for someone with a software engineering background who thrives on transforming early-stage ML prototypes into scalable, production-ready applications.You’ll work alongside a team of brilliant machine learning scientists who are developing compelling tools for therapeutic and diagnostic applications. Your role is to take those V1 alpha-stage prototypes—already scientifically validated—and bring them to life as polished, secure, reliable software tools ready for internal or clinical deployment.
Key Responsibilities
- Productionize ML prototypes: Translate alpha-stage tools (e.g. Jupyter notebooks, python packages) into scalable, secure, and maintainable production systems.
- Full-stack engineering: Build and integrate both back-end services and front-end interfaces that are performant and user-friendly.
- Cloud and GPU infrastructure: Design and deploy applications using GPU-accelerated cloud infrastructure (AWS); including multi-GPU inference using frameworks such as vLLM and DeepSpeed for serving large-scale foundation models.
- AI Model Lifecycle: Oversee the full model lifecycle with versioning (MLFlow), performance monitoring (W&B), and updating strategies (A/B testing).
- Autonomous development: Operate independently with minimal oversight, taking ownership from handoff to final deployment, and iteratively improving products based on internal and external feedback.
- Cross-functional collaboration: Work closely with ML scientists, product leads, and clinical stakeholders to align engineering implementation with scientific and clinical goals.
- DevOps & CI/CD: Set up and manage robust CI/CD pipelines, monitoring tools, and testing frameworks to ensure reliability and reproducibility.
- Security & Compliance: Ensure that tools are developed with appropriate authentication, data privacy, and (where needed) HIPAA or regulatory compliance considerations.
Qualifications
- 5+ years of experience in software engineering, ideally with a focus on ML or scientific computing.
- Proven experience taking ML models or tools from prototype to production in a cloud environment.
- Deep proficiency with:
- Python, Flask/FastAPI or Django (for APIs/services)
- JavaScript/TypeScript with React or similar (for front-end interfaces)
- Cloud platforms like AWS, GCP, or Azure (especially GPU usage)
- Production-scale, multi-GPU AI inference frameworks like vLLM and DeepSpeed.
- Docker, Kubernetes, and related container/orchestration technologies
- Experience with experiment tracking, model registry, and observability tools (e.g., MLflow, W&B) is highly desired.
- Familiarity with model-serving tools (e.g., Triton, TorchServe, TensorFlow Serving) is a plus.
- Experience working in a regulated or health-tech environment is a bonus, but not required.
- Demonstrated ability to work autonomously and prioritize in a fast-paced, interdisciplinary environment.
Preferred Qualities
- Product mindset with an eye for usability, performance, and security.
- Comfortable reading scientific code and engaging with ML researchers.
- Passion for health innovation, biotech, or clinical impact.
- Experience building internal tools or developer platforms is a plus.
Why Join Us?
- Be part of a cutting-edge team shaping the future of AI in healthcare.
- Collaborate with world-class scientists and innovators.
- Build products that could have a direct clinical and therapeutic impact.
- Work in a startup-like environment within a well-established biotech company.
#LI-TH1 #LI-Remote
The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.Remote USA$163,200—$204,000 USD
OUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other.
When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!For more information, visit www.natera.com.Natera is proud to be an Equal Opportunity Employer.
We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status.
We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.If you are based in California, we encourage you to read this important information for California residents. Link: https://www.natera.com/notice-of-data-collection-california-residents/Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team.
Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.For more information:- BBB announcement on job scams- FBI Cyber Crime resource page
