Company Overview
Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugate therapies. Our pipeline includes varegacestat, a late-clinical stage GSI; IM-1021, a clinical-stage ROR1 ADC; and IM-3050, a FAP-targeted radiotherapy that recently received IND clearance.
We are also advancing a broad portfolio of early stage ADCs pursuing undisclosed solid tumor targets.
Position Overview
As a Research Associate III at Immunome, Inc., you will be a key contributor to our research and development initiatives, driving the optimization and delivery of antibody-drug conjugates (ADCs). In this role, you will design, produce, and characterize ADCs in support of program-specific objectives, while collaborating closely with cross-functional partners. Your expertise in bioconjugation will provide critical insights that help advance our therapeutic pipeline and strengthen our scientific capabilities.
Responsibilities
Research Design and Execution
- Generate high quality ADCs to enable advancement of named programs.
- Evaluate innovative bioconjugation and linker technologies.
- Assess developability of discovery stage ADCs.
- Work collaboratively with cross-functional teams to plan experiments aimed at advancing drug development projects.
- Independently perform laboratory experiments in accordance with established protocols, maintaining the highest standards of scientific rigor, documentation, and data integrity.
- Continuously optimize laboratory processes to improve workflow efficiency, reproducibility, and throughput.
- Manage ADC inventory and coordinate delivery of samples to cross-functional partners.
- Data Analysis and Interpretation:
- Characterize biophysical properties of ADCs using various techniques, such as analytical SEC, HIC, PLRP, and LC-MS.
- Interpret results and draw meaningful conclusions to guide decision-making.
Project Collaboration
- Collaborate with colleagues from diverse scientific disciplines to achieve project goals.
- Participate in project team meetings, providing expertise and insights to drive projects forward.
Continuous Learning and Development
- Stay informed about the latest bioconjugation advancements in the ADC field.
- Proactively seek opportunities for professional development and contribute to the scientific growth of the research team.
Qualifications
- BS or MS in Biochemistry, Chemistry, or related field.
- Minimum of 5 years of experience (or 3 years of experience for MS) in preclinical drug development in the biotechnology or pharmaceutical industry.
- Proficiency in bioconjugation techniques and demonstrated experience in ADC pre-clinical development is a requirement.
Knowledge and Skills
- Proficient in analytical techniques and purification methods relevant to biologics and ADC development (SEC, HIC, PLRP, and LC-MS, etc).
- Experience in antibody engineering and protein modification is a plus.
- Excellent communication skills, both written and verbal, to effectively collaborate with cross-functional teams and communicate scientific concepts to non-scientific stakeholders.
- Proven ability to adapt to changing priorities and work in a fast-paced, dynamic environment.
- Experience with Agilent OpenLab and Benchling is a plus.
Please note, the internal title for this role is Research Scientist II, Bioconjugation ChemistryWashington State Pay Range$96,044 - $107,008USD
E/E/O
Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
E-Verify
Immunome, Inc. is a participant in E-Verify. Please review the following notices: E-Verify Participation Poster | Right to Work Poster (English) | Right to Work Poster (Spanish).
