Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.
Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration.
To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.
Executive Director, Thought Leader Liaisons (TLLs)
National Hepatology & GI TLL Team – Madrigal Pharmaceuticals
Remote | ~60–75% Travel
About the Role
We are seeking an experienced, strategic, and people-centered leader to serve as our Executive Director of Thought Leader Liaisons (TLLs). This national, second-line leadership role will lead the Hepatology/GI TLL organization and plays a central role in shaping how Madrigal engages Thought Leaders across the country.Reporting to the Vice President of TLLs, you will help translate national strategy into impactful TLL field execution, elevate organizational capabilities, and develop high-performing leaders who support one of the most meaningful launches in hepatology.This is a rare opportunity to influence a therapeutic category, shape a growing organization, and lead the team that serves as Madrigal’s face to the Hepatology and GI Thought Leader community.
Key Responsibilities
National Leadership & People Development
- Lead and develop a team of Senior Directors of TLLs across the U.S.
- Build a culture of accountability, strategic thinking, and continuous professional development.
- Oversee performance management, capability building, and succession planning for the TLL organization.
Strategic Partnership & Execution
- Serve as a senior thought partner to the VP of TLLs on national strategy, deployment, and continuous innovation.
- Translate strategy into clear, consistent execution plans across zones and teams.
- Guide leaders in identifying opportunities, refining tactics, and ensuring field excellence.
Thought Leader Engagement Excellence
- Lead national Hep/GI TLL execution to accelerate the launch of Resmetirom and ongoing lifecycle preparedness.
- Ensure high-quality Thought Leader engagement and timely, actionable insights.
- Monitor KPIs, performance trends, and field feedback to drive improvements and consistent excellence.
Cross-Functional Collaboration
- Partner closely with Marketing, Market Access, Sales, Medical Affairs to ensure integrated customer engagement.
- Collaborate closely with the National Endocrinology Senior Director of TLLs to ensure cohesive, coordinated ways of working at the field level, especially within shared accounts and institutions.
- Represent the TLL function in cross-functional forums and help ensure alignment across the organization.
Resource & Capability Development
- Inform and co-lead the creation, optimization, and deployment of field tools, training, and processes that elevate TLL effectiveness.
- Integrate real-world insights into continuous improvement of resources and field capabilities.
Qualifications
Required
- Bachelor’s degree (advanced degree preferred).
- 15+ years progressive commercial or field experience in pharma/biotech.
- Minimum of 4 yearsleading TLL teams, including leadership of leaders (national or second-line highly preferred).
- Track record of success in specialty product launches and complex field execution.
- Deep understanding of the Hepatology, GI, or metabolic disease Thought Leader ecosystem.
- Exceptional people leadership, executive presence and communication, strategic thinking, and organizational development skills.
- Strong business acumen and ability to translate strategy into operational plans.
- Commitment to compliance and ethical engagement.
Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands.
The base salary range for this position is $276,000 to $338,000 per year.All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization. Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans.
We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws. We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com. Madrigal is an Equal Opportunity Employer.
All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law. Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source.
Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established. Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site. Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates.
Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process. Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners.
We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to HR@madrigalpharma.com.
