The successful candidate will be an essential part of the Research team focusing on the design, implementation, and oversight of in vivo pharmacology studies leading to successful FDA IND application(s) of FIC/BIC biologics, including multispecific in immunology and inflammation. The position will lead a small but motivated in vivo team. The job will require collaboration with cross functional partners to manage resource allocations to enable portfolio progression. Projects requiring pharmacology support may span from target validation, preclinical development, to translational biology. This is a full-time position reporting directly to the Chief Scientific Officer. The role is onsite preferred.
Key Responsibilities
- Provide leadership in preclinical pharmacological program development from target validation to successful regulatory filings for mono- and multispecific biologics.
- Management of all in-vivo pharmacology studies, including design, implementation, conduct and reporting.
- Facilitate the conceptualization and development of innovative research strategies and plans for preclinical studies aligned with the company's therapeutic portfolio and goals.
- Identifying, assess, and oversee various contract research organizations (CRO’S) to complement internal capabilities and generate critical pharmacokinetic, pharmacodynamic, and efficacy data.
- Foster effective collaboration and communication with internal teams, external partners, and key stakeholders to ensure alignment of research objectives and facilitate knowledge sharing.
- Perform independent research within the field of study to provide leadership to advance optimization of the in vivo research methodologies, technologies, and industry trends.
- Develop and present Pharmacology strategy, plans and data at project team meetings and to management to support project objectives.
- Support the filing of regulatory documents, including preparation of final study reports and IND (or related) documents
- Contribute to a team culture that promotes collaboration, open communication, career development, excellence, ownership, curiosity, and inclusion.
Qualifications
- PhD in Molecular & Cell Biology, Genetics, Biochemistry, Immunology, Physiology or related areas.
- Minimum 15 years of experience designing, executing, and overseeing in vivo pharmacology studies to support projects in the pharmaceutical or biotech industry with an emphasis on in vivo models of immunology and inflammation in the gut, skin and respiratory organs and autoimmune diseases.
- Minimum 10 years of experience managing teams and representing Pharmacology on cross-functional teams.
- Experience in generating and managing pre-IND reports is strongly preferred.
- Prior experience with biologics drug discovery and development is preferred.
- Previous experience working in fast paced start-up environments preferred.
Technical Requirements and Skills
- Strong technical expertise in study design methodologies, a wide range of in vivo autoimmune and inflammatory disease models.
- A strategic thinker with the ability to analyze possibilities, evaluate the benefits/risks as well as mitigation strategies and solutions.
- Strong leadership, program management skills, including experience in building, leading and developing strong and collaborative scientific teams.
- Strong communication skills, with the ability to effectively collaborate with cross-functional teams and external partners.
- Demonstrated ability to stay updated with the latest advancements and trends within in vivo research.
- Must be proactive and able to work effectively on multiple projects in a fast-paced, dynamic environment.
- Strong written and verbal communication skills.
$270,000 - $300,000 a yearLeveling and salary is commensurate with experience.
About Attovia
Attovia is creating a pipeline of biotherapeutics with initial focus immune-mediated disease. The company leverages Attobody™, a novel biologics platform, to generate small format biparatopic binders that expand the addressable target universe across disease areas and can offer stronger efficacy, faster speed to response, and an improved safety profile than traditional approaches. We are currently progressing multiple programs across immune-mediated disease indications.Our culture is centered around five core pillars: • Integrity • Learning & Growth • Drive for Excellence • Innovation • Teamwork & Collaboration We take pride in fostering a strong team and dynamic work environment, and we are seeking individuals who align with our values and contribute to a positive and impactful workplace. Attovia is located in San Carlos, CA.Attovia is an equal opportunity employer.
All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. Learn more about Attovia: www.attovia.comWe may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans.
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