Mavericks Wanted
When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read onIn 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible. Together we define white space, push boundaries and empower people to solve problems.
If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma.
What You'll Do
Maverick wanted! We’re seeking a Sr. Director, Data Science, Patient Identification who thrives at the frontier of machine learning/statistical modelling, healthcare data, and translational analytics. You’ll develop approaches and models (AI/ML/traditional statistics) that find patients, detect disease patterns that are indicative of an undiagnosed rare disease, shape data strategies, and feed targeting engines that directly change patients' and families' lives. In this role, you’ll shape and lead data-driven strategies to uncover undiagnosed patients, accelerate diagnosis, and drive smarter decisions across our rare disease portfolio.
If you’re passionate about using data science to drive tangible patient outcomes, this is where you belong.
Responsibilities
Strategic Data Science Leadership
- Spearhead a high-performing data science function focused on patient identification and provider targeting
- Identify, source, and integrate (tokenized) data assets in the pursuit of finding rare disease patients and treating HCPs across the portfolio for BrigeBio companies. Define the vision, priorities, and key success metrics for data science initiatives across multiple rare disease programs
- Architect scalable analytical solutions using RWD (claims, EHR, genomics, lab data, imaging, and registry sources)
- Define the roadmap for AI/ML innovation, balancing cutting-edge research with production-grade reliability
- Build and foster a collaborative, mission-driven culture grounded in an enterprise perspective (use of data and data science work across the organization), precision, urgency, and patient impact
Advanced Analytics & Machine Learning
- Design predictive models, algorithms, and patient finding tools using real-world data (claims, EMR, lab/genomics). Apply NLP and LLM techniques to extract phenotypic signals from unstructured EMR data
- Pioneer new methodologies in AI/ML for patient identification, leveraging subtle clinical and diagnostic patterns. Design and execute experiments with different approaches to patient finding
- Build frameworks for model monitoring, retraining, and performance evaluation in real-world deployment environments
- Design and deploy supervised and unsupervised models for patient finding, diagnostic acceleration, and disease progression prediction. Translate complex insights into actionable strategies for field execution, engagement planning, and clinical partnerships
Data Strategy & Infrastructure
- Drive the development of robust data pipelines, governance frameworks, and scalable model-serving infrastructure
- Evaluate and integrate third-party data (claims, genomics, HCP, diagnostic lab feeds) to enhance model accuracy and reach
- Partner with outside vendors and internal resources to operationalize analytics solutions across BridgeBio’s portfolio
- Champion best practices in reproducibility, version control, and MLOps
Cross-Functional Collaboration
- Partner with Commercial, Medical Affairs, and Computational Genomics teams to integrate analytic insights into decision-making
- Engage with KOLs and data partners to identify early clinical signals that inform algorithmic models
Operational Excellence
- Establish program-level KPIs, dashboards, and reporting frameworks to track performance and continuously improve model accuracy
- Ensure compliance with HIPAA, privacy, and ethical data governance standards
- Manage external vendors and partnerships to expand analytic capabilities and accelerate delivery
Where You'll Work
3x per week in our San Francisco Office/Palo Alto Office.
Who You Are
Required
- 10+ years of experience in data science or analytics within biotech/pharma; 3+ years in a leadership role
- Proven expertise in real-world data (RWD) analytics, patient identification, and segmentation across multiple therapeutic areas. Experience with large-scale real-world data (claims, EMR/EHR, lab/genomics, registry, or wearable data)
- Experience developing and deploying sophisticated ML/statistical models using large-scale health data. Deep expertise in building predictive and classification models using Python, R, SQL, TensorFlow, PyTorch, or equivalent tools. Strong understanding of feature engineering, model explainability, and ML pipeline automation
- Proven success translating analytics into actionable strategies that drive measurable patient or business outcomes
- Bachelor’s degree in data science, computer science, statistics, or a related quantitative field
- Experience in rare disease analytics or patient-finding programs that supported commercial launches or diagnostic initiatives
Preferred
- Advanced degree (PhD, MS, MPH) in data science, biostatistics, computer science, or related field
- Familiarity with generative AI, LLMs, or graph-based learning applied to healthcare or biomedical data
Rewarding Those Who Make the Mission Possible
We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.
Financial Benefits:
- Market leading compensation
- 401K with 100% employer match on first 3% & 50% on the next 2%
- Employee stock purchase program
- Pre-tax commuter benefits
- Referral program with $2,500 award for hired referrals
Health & Wellbeing:
- Comprehensive health care with 100% premiums covered - no cost to you and dependents
- Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)
- Hybrid work model - employees have the autonomy in where and how they do their work
- Unlimited flexible paid time off - take the time that you need
- Paid parental leave - 4 months for birthing parents & 2 months for non-birthing parents
- Flex spending accounts & company-provided group term life & disability
- Subsidized lunch via Forkable on days worked from our office
Skill Development & Career Paths:
- People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
- We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching
- We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities
At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process.
BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.Salary$260,000 - $300,000USD