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Senior Systems Engineer

CompanySynthego
LocationRedwood City, California, United States
TypeHybrid, Onsite
Synthego is seeking a skilled and forward-thinking IT Systems Engineer to help design, implement, and optimize the technology foundation that powers groundbreaking CRISPR research. This is a pivotal opportunity to advance innovation in life sciences by ensuring our scientists and engineers have secure, reliable, and high-performance systems at their fingertips. You will architect and support critical infrastructure, streamline operations, and deliver seamless user experiences across a hybrid environment. If you 
thrive at the intersection of engineering, IT, and science—pushing technology to enable discoveries that improve human health—this role is for you.

What You'll Do:


  • Design, implement, and optimize secure, scalable IT solutions across a modern SaaS-first environment.
  • Lead projects that align technology with business outcomes, improving efficiency, collaboration, and security.
  • Administer and enhance critical platforms including Microsoft 365, Okta, AWS, Slack, and AI-enabled tools.
  • Manage and support core network and security infrastructure such as Fortigate firewalls, Meraki networking, and VPN services.
  • Oversee virtualization environments, including VMware, to ensure reliable and cost-effective compute resources.
  • Drive automation and process improvements to streamline IT operations and reduce manual effort.
  • Serve as an escalation point for complex support issues, ensuring timely resolution and minimal disruption.
  • Partner with scientists, engineers, and business stakeholders to translate research and operational needs into technical solutions.
  • Maintain strong security practices, including identity and access management, endpoint controls, and incident response readiness.
  • Document systems, processes, and standards to support scalability, compliance, and knowledge sharing across the team.

About You:


  • BS or equivalent degree in Computer Science, Information Systems, or related field
  • 5+ years of experience as a Systems Engineer, IT Administrator, or similar technical role
  • Proven expertise managing SaaS platforms such as Microsoft 365, Okta, Slack, and other business-critical applications
  • Hands-on experience with networking and security technologies (e.g., Fortigate, Meraki) and on-premises and cloud infrastructures (AWS, VMware)
  • Strong understanding of identity and access management, security best practices, and compliance requirements
  • Excellent troubleshooting skills with experience serving as an escalation point for complex issues
  • Adept at project execution—able to translate business needs into technical solutions that drive measurable results
  • Strong communication and collaboration skills, with the ability to partner effectively across technical and non-technical teams
  • Analytical and process-oriented, with a continuous improvement mindset and a focus on automation where possible
  • Self-starter who thrives in a fast-paced, evolving environment and is comfortable balancing strategic projects with hands-on problem-solving

Company Perks & Benefits


  • Medical, dental, and vision benefits
  • 401k Program
  • Paid parental leave
  • Flexible paid time off

$135,000 - $155,000 a yearRate offered will be based on experience.

Our Mission


Synthego® is a pioneering force in the biotechnology industry, dedicated to advancing the frontiers of CRISPR cell and gene therapies through cutting-edge CRISPR technology and expertise. Our mission is to provide unparalleled access to CRISPR solutions at scale, empowering applications from Discovery to Clinic. Driven by a visionary approach, we strive to accelerate the therapeutic development process with best-in-class CRISPR solutions, simplified licensing & expert guidance, driving the adoption and success of CRISPR-based therapies to benefit all patients.We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses.

These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.Apply for this job

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