Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. This is an exciting time to join Crinetics as we shape our organization into the world’s premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others.
Position Summary:
The Executive Director, Global Facilities Operations and EH&S is a senior leadership role responsible for developing and executing the global strategy for facilities management and environmental health & safety across all corporate and R&D sites. This role ensures operational excellence, regulatory compliance, and a culture of safety and sustainability that supports the company’s mission.The ideal candidate will be a visionary leader with deep expertise in facilities operations, EH&S programs, and organizational leadership within a regulated biotech or pharmaceutical environment.
Essential Job Functions and Responsibilities:
These may include but are not limited to:
Strategic Leadership & Governance:
- Serve as the primary advisor to executive leadership on matters related to real estate, site operations, and EH&S risk, offering strategic guidance and actionable insights.- Define and communicate the global strategy for facilities operations and EH&S, ensuring alignment with corporate objectives and long-term growth plans.- Present long-range strategic plans and infrastructure recommendations to senior leadership for review and decision-making.- Direct planning efforts for site development, space optimization, and capital investment prioritization.- Establish and maintain governance frameworks, performance metrics (KPIs), and reporting systems to support continuous improvement and operational accountability.
Global Facilities Operations:
- Manage all aspects of facilities operations across corporate and R&D sites, including maintenance, utilities, infrastructure, and space planning.- Lead capital projects and renovations, ensuring alignment with business needs, timelines, and budgets.- Develop and manage the global multi-year operating and capital budgets for facilities and EH&S, ensuring alignment with corporate financial targets.- Present financial plans and major capital investment proposals to the executive leadership.- Champion workplace experience initiatives, including sustainability, ergonomics, and employee well-being.- Lead planning and execution of ex-US facility expansion projects, including site selection, regulatory alignment, and integration with global operations.- Oversee physical security programs and infrastructure to ensure the safety and protection of all sites and personnel.
Environmental Health & Safety (EH&S):
- Develop and implement global EH&S policies, standards, and training programs to ensure a safe and compliant work environment.- Ensure adherence to international, federal, state, and local regulations (e.g., OSHA, EPA, Cal/OSHA, EU-OSHA, ISO).- Lead risk assessments, incident investigations, and corrective action planning.- Oversee programs for chemical safety, biosafety, radiation safety, and potent compound handling.- Collaborate with scientific and operational teams to ensure EH&S integration into research workflows.
Team Leadership & Collaboration:
- Build and lead a high-performing global team of facilities and EH&S professionals.- Foster cross-functional collaboration with R&D, Quality, HR, Legal, IT, and other departments to support operational readiness and business continuity.- Represent the company in regulatory inspections, external audits, and industry forums.
Risk Management & Sustainability:
- Identify and mitigate risks related to infrastructure, safety, and environmental impact.- Drive sustainability initiatives including energy efficiency, waste reduction, and green building practices.- Lead the development and reporting of Environmental, Social, and Governance (ECG) initiatives related to facilities operations.- Maintain and enhance emergency preparedness and business continuity plans.
Education and Experience:
Required:- Bachelor’s degree in Engineering, Environmental Science, Occupational Safety, Facilities Management, or a related field.- Minimum 15 years of progressive leadership experience in operations, with at least 10 years spent managing global or multi-site functions and teams- Proven success in managing multi-site operations and leading global teams.- Strong knowledge of regulatory compliance frameworks including GMP, GLP, and EH&S standards.- Excellent leadership, communication, and stakeholder engagement skills.Preferred:- Professional certifications such as CSP, CIH, LEED AP, PMP, or Six Sigma are highly desirable.- Strong knowledge of regulatory compliance frameworks including GMP, GLP, and EH&S standards, with direct experience in the design, construction, or management of GMP-compliant manufacturing or laboratory facilities highly preferred.
Physical Demands and Work Environment:
Physical Activities: On a continuous basis, sit at desk for a long period of time; intermittently answer telephone and write or use a keyboard to communicate through written means. Some walking and lifting up to 25 lbs. may be required. The noise level in the work environment is typically low to moderate. The physical demands described above are representative of those that must be met by an employee to successfully perform the essential functions and responsibilities of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions and responsibilities.Laboratory Activities (if applicable): Biology and chemical laboratory environment experience needed.
Environmental health and safety requirements also apply.
Travel:
You may be required to travel for up to 5% of your time.
Equal Opportunity Employer:
Crinetics is proud to be an Equal Opportunity Employer. We provide equal employment opportunities to all employees and employment applicants without regard to unlawful considerations of sex, sexual orientation, gender (including gender identity and/or expression), pregnancy, race, color, creed, national or ethnic origin, citizenship status, religion or similar philosophical beliefs, disability, marital and civil union status, age, genetic information, veteran status or any personal attribute or characteristic that is protected by applicable local, state or federal laws.
Total Compensation:
The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience and education. Crinetics Pharmaceuticals is a multi-state employer, and this salary range may not reflect positions that work in other states. Your recruiter can share more about the specific salary range during the hiring process.
Salary RangeThe salary range for this position is: $250,000 - $312,000.
In addition to your base pay, our total rewards program consists of a discretionary annual target bonus, stock options, ESPP, and 401k match. We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown.
