Job Overview
BPS Bioscience Inc. is a leading provider of recombinant proteins, assay kits, and recombinant cell lines for drug discovery. We are seeking an exceptional scientist, with a strong background in enzymology, enzyme kinetics, protein/protein interactions, and fluorescence and luminescence-based assays.We are seeking a highly skilled Senior Scientist I with deep expertise in antibody generation to join our Molecular and Cellular Biology team. This position plays a critical role in driving research and development efforts, with a primary focus on the design, expression, engineering for multiple targets, purification, and optimization of antibodies, including phage display, single B cell isolation, humanization, and stable cell line generation.
The ideal candidate will have strong industry experience and be adept at independently designing and executing experiments at a high standard.Responsibilities:
- Lead and execute projects related to antibody generation, including:
- Antibody design and engineering (e.g., humanization, affinity maturation, bispecific antibody)
- Molecular cloning and vector design
- Transient and stable expression in mammalian system
- Antibody purification using affinity chromatography and other techniques
- Develop and optimize stable cell lines for antibody production
- Utilize fermentation systems for antibody expression (small- to mid-scale)
- Evaluate and integrate new technologies to enhance R&D capabilities
- Participate in team meetings, project planning, and cross-functional collaborations
- Design and perform cell-based functional assays to characterize antibody activity
- Present research findings internally and externally, including at scientific conferences
- Maintain rigorous documentation and ensure high standards of data integrity
- Maintaining excellent working relationships with partners throughout the company.
- Maintaining updated and well-organized lab notebooks.
- Other tasks and duties as assigned.
Requirements:
- A Ph.D. degree in Molecular Biology, Cell Biology required.
- Minimum 3 - 5 years industry experience focused on antibody generation required
- The candidate must have proven experience performing enzyme kinetics and assay optimization.
- Proven track record in antibody discovery and development, including engineering and functional validation
- Extensive experience with phage display, mammalian cell culture, sterile technique, and molecular biology methods
- Proficiency in downstream processing including protein purification and analytical characterization
- Strong problem-solving skills and ability to manage multiple projects in parallel
- Excellent written and verbal communication skills
- Team-oriented with a collaborative mindset and attention to detail
Benefits!
- 401k with 4% company match
- Medical/Dental/Vision health insurance plans
- Vacation and paid holidays
- Companywide lunches provided quarterly
BPS Bioscience is an equal opportunity employer, without regard to race, color, religion, age, gender, sexual orientation, disability, or any other characteristic protected by applicable law.
