logo inner

Sr. Consultant / mRNA engineering

GenEditSouth San Francisco, California, United StatesHybrid, Onsite
This job is no longer open

Job Description


GenEdit is a rapidly growing, early-stage company that is developing a proprietary and novel delivery platform with the potential to transform genetic medicine. Our interdisciplinary team works together across chemistry, payload, formulation, screening, and preclinical groups to develop the next generation of gene therapies. GenEdit fosters an exciting and dynamic environment where we value impactful data and creative solutions to accelerate our progression from platform technology to a pipeline of therapeutic candidates.We are seeking a Sr.

Consultant with deep expertise in mRNA engineering to help our cross-functional discovery teams and create novel drug candidates.

Key Responsibilities


·Design and optimize mRNA sequences including 5′ and 3′ untranslated regions (UTRs) and open reading frames (ORF) to enhance mRNA's stability, translation efficiency, and ultimately, therapeutic effect.·Design and polycistronic mRNA encoding multiple protein/peptide antigens.·Implement novel methods for mRNA modifications to improve its therapeutic potential.·Use mRNA design software to support mRNA design workflows and to analyze data and predict the behavior of designed mRNA constructs.·Generate intellectual property and contribute to regulatory filings.·Keep up-to-date with new technologies, industry trends, and research in mRNA science. 

Qualifications


·PhD degree in molecular biology or a closely related discipline with 10+ years of experience·Extensive experience in mRNA design, including expertise in designing, modifying, and optimizing RNA molecules.·Proficiency with computational tools, including relevant software, algorithms, and databases for mRNA design and analysis.·Industry experience in mRNA design or related areas is highly preferred·Ability to analyze and interpret complex data from experiments and computational analysis.·Excellent written and verbal communication skills At GenEdit we are always looking to hire the absolute best talent and recognize that diversity in our experiences and backgrounds is what makes us stronger.

We hire candidates of any race, color, ancestry, religion, sex, national origin, sexual orientation, gender identity, age, marital or family status, disability, veteran status, and any other status. These differences are what enable us to work towards the future we envision for ourselves, and the world.Apply for this job

This job is no longer open

Life at GenEdit

GenEdit is a next-generation genome editing company. We are developing non-viral delivery technologies for the CRISPR/Cas9 gene editing system that can safely and efficiently correct gene mutations in patients. CRISPR/Cas9 is a powerful genome editing tool that makes therapeutic gene editing possible. It is easier to use, faster, and more accurate than previous gene editing techniques and thus has the potential for a wide range of therapeutic applications. In particular, CRISPR/Cas9 gene editing has the potential to treat a variety of incurable genetic diseases. However, current CRISPR delivery methods rely on viruses and are problematic due to viral-induced toxicity and prolonged Cas9 exposure, increasing off-target effects. A non-viral CRISPR/Cas9 delivery method is needed. In addition, low efficiency levels achieved make it impossible to target certain diseases. GenEdit's novel CRISPR delivery technology has the potential to be a platform delivery system for a broad range of genetic diseases. We also work on engineering of core components of CRISPR/Cas9 genome editing system to increase editing efficiency and enable targeted delivery.
Thrive Here & What We Value1. Dynamic and exciting environment2. Valuing impactful data and creative solutions3. Emphasis on teamwork and collaboration4. Commitment to advancing novel therapies in genetic medicine5. Diversity as a strength6. Inclusive hiring practices
Your tracker settings

We use cookies and similar methods to recognize visitors and remember their preferences. We also use them to measure ad campaign effectiveness, target ads and analyze site traffic. To learn more about these methods, including how to disable them, view our Cookie Policy or Privacy Policy.

By tapping `Accept`, you consent to the use of these methods by us and third parties. You can always change your tracker preferences by visiting our Cookie Policy.

logo innerThatStartupJob
Discover the best startup and their job positions, all in one place.
Copyright © 2025