About The Role:
The Associate Scientist II, Process Development – Upstream plays a critical role in supporting the development and optimization of AAV manufacturing processes. This individual will closely with cross-functional teams to lead and execute experiments, collect and analyze data, and contribute to the overall development of scalable AAV production processes.
What You'll Do:
- Lead the design, planning and execution of experiments for AAV upstream process development.
- Independently operate and troubleshoot bioreactors and other upstream equipment.
- Optimize cell culture and transfection processes to improve AAV yields and quality.
- Analyze and interpret complex experimental data, identifying trends, and suggesting improvements.
- Assist in the training and guidance of new team members.
- Develop and revise standard operating procedures (SOPs) and batch records.
- Assist in maintaining proper inventories of raw materials and consumables.
- Prepares formulations and raw materials as specified in protocols without the introduction of contaminants.
- Collaborate with cross-functional teams to transfer and scale up processes for manufacturing.
- Participate in equipment maintenance and calibration activities.
What You'll Bring:
- Bachelor’s Degree in Chemical Engineering, Biomedical Engineering, Biology, or related discipline (or equivalent experience).
- Working knowledge of cell culture techniques utilizing mammalian, insect, or microbial cells.
- Prior suspension cell culture experience utilizing shake flasks or bioreactors.
- Experience conducting and compiling experimental data with minimal oversight.
Preferred Experience:
- Master’s Degree in Chemical Engineering, Biomedical Engineering, Biology, or related discipline.
- Experience working with viral vectors (AAV, Lentivirus, etc.).
Physical Requirements:
This position works in both a laboratory environment and typical office environment where the physical work demands will vary depending on the specific tasks and duties required of the job. The employee will be stationary (standing/sitting) for extended periods of time. Employees regularly wear personal protective equipment based on the task being performed. Must be able to work in a confined space, such as a clean room or laboratory environment. Ability to identify small details within the field of vision, distinguish between different colors, and accurately identify objects within a specific area. This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee.
Duties, responsibilities and activities may change or new ones may be assigned.Forge Biologics is an equal opportunity employer dedicated to building an inclusive and diverse workforce. Forge Biologics, provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
Life at Forge
We are a team of diverse, driven and passionate people working together to trailblaze a new model for how we make medicines to treat patients with genetic diseases.Our team members use their creativity and talent to invent new solutions, meet new demands, and offer the most effective services in the industry. Forge’s core values lay the foundation for H.O.P.E. It provides us a common purpose that we all understand, work towards and live by.
H
ARDWORKING - We work hard and smart, making a persistent and determined effort toward success. Working hard, with focus and desire is the key.
O
PEN - We strive to be approachable, actively listen and encourage others to contribute and speak up. We positively offer and receive constructive feedback.
P
URPOSE DRIVEN - We are passionate about working towards and delivering on our mission to manufacture gene therapies.
E
NGAGED - We are fully absorbed by and enthusiastic about our work and take positive action to further Forge’s vision, mission and goals.
We’ve Got You Covered
We take the health and happiness of our employees seriously and are consistently evaluating new ways to make our benefits truly Un
FORGE
ttable.Health, Dental, and Vision insurance that starts on your first day at Forge, with 90% of premiums covered for team members as well as dependentsCompetitive paid time off planAnnual bonus for all full-time employees401(K) company matchFully-stocked kitchen with free food/drinks12 weeks of paid parental leave - additional discount programs include childcare support & dependent careEmployee Assistance Program Wellness benefits (financial planning services, mental health counseling, employer paid disability)Onsite fitness facility Professional & Personal development resources
