Who we are
At Abdera Therapeutics, we are on a mission to revolutionize cancer treatment. Leveraging our proprietary ROVEr™ platform, we engineer precision radiotherapeutics that finely tune radioisotope delivery to maximize therapeutic effects while sparing healthy tissue. Our innovative approach holds the potential to transform the treatment of a broad range of solid tumors. Abdera’s lead program, ABD-147, is a next-generation precision radiopharmaceutical biologic therapy in Phase 1 clinical development and is designed to deliver Actinium-225 (225Ac) to solid tumors expressing delta-like ligand 3 (DLL3) for the treatment of small cell lung cancer (SCLC) and large cell neuroendocrine carcinoma (LCNEC).
Our company, technology, and team are purpose-built to attack cancer head-on. Led by a dynamic team of scientists and industry veterans with extensive experience in oncology, radiopharmaceuticals, and biologics, we are united by a shared passion for cutting-edge science and a relentless pursuit of optimized therapies for people living with cancer.
What we look for
At Abdera Therapeutics, we are looking for curious and committed individuals who are ready for the opportunity to transform the way people living with cancer can be treated. We are devoted to advancing novel treatment options that offer new hope to families facing devastating diagnoses. We are in search of team members who work collaboratively with a diverse group of colleagues, respectfully engaging one another while collectively and inclusively tackling any challenges we may face. We are building an exciting and fast paced company passionate about discovering and developing tomorrow’s most innovative cancer therapies.
Salary range - Vancouver - 165k - 205kSalary range - SF Bay area 175k - 215k
Principal Responsibilities
- Develop and implement bioanalytical strategies to evaluate PK, PD, metabolites biomarkers and immunogenicity to support preclinical and clinical studies.
- Provide scientific and technical oversight by leading activities in house and at contract research organizations (CROs) in bioanalytical assay design, method development, optimization, validation, sample analysis, lifecycle support and custom reagent generation.
- Identify new assays and technologies to expand bioanalytical capabilities that contribute to developing radiopharmaceuticals as cancer therapies.
- Lead, develop, and train members of the bioanalytical team and plan for resourcing needs.
- Evaluate and review data, protocols and reports and ensure documentation is accurate and complete, adhering to regulatory guidelines where appropriate.
- Contribute to authoring regulatory filings and manuscripts.
- Collaborate with cross-functional team members to provide bioanalytical expertise, present data and advance programs.
Qualifications, Education & Experience
- PhD in Cell and/or Molecular Biology, Biochemistry, Biophysics, Immunology, Pharmacology or related disciplines with 12+ years of relevant experience, or an equivalent combination graduate education and industry experience.
Skills and Abilities
- Track record and expertise with developing and implementing bioanalytical strategies and methods for antibody-based therapeutics.
- Demonstrated advanced knowledge and technical hands-on experience in bioanalytical techniques, including ELISA, MSD and BLI-based assays.
- Direct experience leading teams, evaluating and managing CROs and developing and maintaining effective working relationships with key partners.
- Competency with analysis methods, statistical analysis and electronic lab notebook software.
- Prior experience preparing documentation for regulatory filings and knowledge of regulatory requirements for bioanalytical assays.
- Proven ability to work collaboratively in a cross-functional team.
- Proven ability to manage concurrent deliverables in a fast-paced, milestone-driven environment.
- Excellent communication and presentation skills.
- Excellent attention to detail and accuracy.
Abdera is an equal opportunity employer that is committed to diversity and inclusion in the workplace. At Abdera, we prohibit harassment of any kind and any form of discrimination including but not limited to discrimination based on race, color, sex, religion, marital status, sexual orientation, national origin, disability, veteran status, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws. This is applicable to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, training, and apprenticeship.
Please include a cover letter and current resume to apply.
