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Senior or Principal Scientist

MaxCyteWaltham | Massachusetts, Massachussets, United StatesOnsite
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Full-timeDescriptionWe are seeking a Senior or Principal Scientist with expertise in gene editing using CRISPR systems to join our R&D team. The candidate will invent, test, and develop novel methods for genome editing and off-target profiling using CRISPR nucleases and base editors. They will also lead the development of advanced approaches for confirmation sequencing and rearrangement analysis. This role will require strong communication skills and the ability to collaborate in a cross-functional manner with automation, bioinformatics, operations, and product development scientists.

  • Invent, implement, and creatively develop advanced next-generation off-target profiling technologies and innovative assays
  • Apply scientific expertise and judgement to initiate, design, execute, and analyze experiments and projects in a time sensitive manner
  • Act as an impactful leader and contributor to project teams
  • Mentor and advise other research scientists
  • Foster creativity, collaboration, and execution with a sense of urgency
  • Work with product development and operations teams to provide technical leadership, and establish SOPs
  • Document results and present to senior management, colleagues, and clients
  • Stay abreast of academic and industry advancements in relevant technology areas 

Requirements

  • Ph.D. in biochemistry, genome editing, molecular biology, genomics, or related field with 4+ years of relevant post-graduate experience in an academic or biotech setting
  • Deep technical knowledge and hands-on experience in high sensitivity genome editing, off-target nomination and confirmation methods, NGS library workflows, and targeted sequencing. 
  • Expert knowledge of analytical methods, statistical analysis tools, sequencing data analysis and interpretation
  • Expertise in experimental design, developing new technology, innovation, and continued process improvement
  • Excellent interpersonal and communication skills
  • Strong problem solving, troubleshooting skills
  • Self-driven, with a strong attention to detail

We offer a competitive base salary, annual bonus, and equity. MaxCyte also offers a comprehensive benefits package including health, dental, vision, life, and disability insurance and generous time off.MaxCyte is an Equal Opportunity Employer.  All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status.

Life at MaxCyte

MaxCyte is a global cell-based medicines and life sciences company applying its patented cell engineering technology to help patients with high unmet medical needs in a broad range of conditions. MaxCyte is developing novel CARMA therapies for its own pipeline. CARMA is MaxCyte's mRNA-based proprietary platform for autologous cell therapy. In addition, through its core business, the Company leverages its Flow Electroporation® Technology to enable its partners across the biopharmaceutical industry to advance the development of innovative medicines, particularly in cell therapy, including gene editing and immuno-oncology. The Company has placed its cutting-edge flow electroporation instruments worldwide, including with nine of the top 10 global biopharmaceutical companies, and has more than 55 partnered program licenses in cell therapy including more than 25 licensed for clinical use. With its robust delivery technology, MaxCyte helps its partners to unlock the full potential of their products. For more information, visit www.maxcyte.com.
Thrive Here & What We Value* Onsite at MaxCyte's headquarters located in Rockville, Maryland* Mondays, Thursdays, or as needed* Absolute discretion and confidentiality regarding sensitive information* Reasonable accommodations for COVID-19 vaccination exemptions on a case-by-case basis* Compliance with applicable law
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