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Research Associate (RA) / Sr. RA, Nanoparticle Formulation and Cell Biology

GenEditSouth San Francisco, California, United StatesOnsite
Research Associate (RA)/Senior RA, Nanoparticle Formulation and Cell Biology
Department: PPDPosition: Full-TimeLocation: Brisbane, CAResearch Associate (RA)/Senior RA, Nanoparticle Formulation and Cell BiologyGenEdit is an early-stage company that is developing a proprietary and novel delivery platform with the potential to transform genetic medicines. Our interdisciplinary team works together across polymer chemistry, payload, formulation, screening, and preclinical groups to develop the next generation of gene therapies and nanomedicines. We foster an exciting and dynamic environment where we value impactful data and creative solutions. 

Responsibilities


We are seeking a talented and motivated individual to join our team in Brisbane, CA, and support the development of genetic medicines utilizing GenEdit’s proprietary hydrophilic nanoparticle (HNP) platform. This position will work full-time in our wet labs to support nanoparticle formulation activities including a variety of physical and biological characterization methods. This position will report to a formulation scientist in our product and process development (PPD) team and will be expected to execute at a high level in the lab, keep detailed lab records, learn new analytical techniques, and cooperate efficiently with other technicians and scientists.

Education and Qualifications


•BS or BA in biological sciences, biotechnology, chemistry, nanomedicines, or a related field•Relevant hands-on lab experience, ideally in an industry setting•Lab experience with standard molecular and cell biology techniques including proper handling of nucleic acids, RNA and DNA characterization (UV-Vis spectroscopy, electrophoresis, and quantitative fluorescence assays, e.g., RiboGreen), mammalian cell culture, and aseptic technique•Excellent communication and organizational skills•Ability to efficiently execute standard operating procedures with precise reproducibility•Preferred experience with nanoparticle formulation, nucleic acid encapsulation methods (microfluidics, T-tube mixing), light scattering and zeta potential instruments (DLS, MALS)•Preferred experience with plate readers, flow cytometry, FlowJo, and electronic lab notebook record keeping•Work authorization in the US is requiredAt GenEdit we are always looking to hire the absolute best talent and recognize that diversity in our experiences and backgrounds is what makes us stronger.

We hire candidates of any race, color, ancestry, religion, sex, national origin, sexual orientation, gender identity, age, marital or family status, disability, veteran status, and any other status. These differences are what enable us to work towards the future we envision for ourselves, and the world.Apply for this job

Life at GenEdit

GenEdit is a next-generation genome editing company. We are developing non-viral delivery technologies for the CRISPR/Cas9 gene editing system that can safely and efficiently correct gene mutations in patients. CRISPR/Cas9 is a powerful genome editing tool that makes therapeutic gene editing possible. It is easier to use, faster, and more accurate than previous gene editing techniques and thus has the potential for a wide range of therapeutic applications. In particular, CRISPR/Cas9 gene editing has the potential to treat a variety of incurable genetic diseases. However, current CRISPR delivery methods rely on viruses and are problematic due to viral-induced toxicity and prolonged Cas9 exposure, increasing off-target effects. A non-viral CRISPR/Cas9 delivery method is needed. In addition, low efficiency levels achieved make it impossible to target certain diseases. GenEdit's novel CRISPR delivery technology has the potential to be a platform delivery system for a broad range of genetic diseases. We also work on engineering of core components of CRISPR/Cas9 genome editing system to increase editing efficiency and enable targeted delivery.
Thrive Here & What We Value1. Dynamic and exciting environment2. Valuing impactful data and creative solutions3. Emphasis on teamwork and collaboration4. Commitment to advancing novel therapies in genetic medicine5. Diversity as a strength6. Inclusive hiring practices
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