Totus Medicines is an innovative therapeutic drug discovery biotech that has developed a platform focused on targeted covalent drugs. This novel proprietary platform will enable Totus to deliver candidates against challenging targets in months, not years – 100,000 times faster than competitive technologies and has the potential to expand the spectrum of drug targets to be screened for any disease process.
Totus discovered its first-in-class covalent program in 4 months and entered Phase I in 2023. Totus also plans to expand their platform to create therapeutics targeted at neurodegeneration, infectious diseases, and others. We are searching for talented, passionate, agile candidates to join our team.We are seeking a self-motivated and detail-oriented Research Associate in the field of protein sciences within the Totus research group. This is a contract position for 6 -12 months.The successful candidate will produce and characterize a wide variety of disease relevant proteins while working in multi-disciplinary team, with ample opportunities to learn cutting-edge science.
Responsibilities and Expectations
- Cell biology: maintain, track, and transiently transfect mammalian cells in parallel
- Protein production: measure overexpression using a variety of techniques
- Harvest: aliquot, store, and inventory host cells for downstream use
- Document results in an ELN in a detailed and timely manner
- Open to learning new techniques
- Actively contribute to a culture of scientific excellence and integrity
Qualifications
- B.S. degree in cell biology, biochemistry, bioengineering, or a related discipline, with 1+ year of laboratory experience
- Strong organizational and communication skills; ability to prioritize tasks and manage time effectively; attention to detail and documentation
- Excellent laboratory and sterile technique
- Hands-on experience with mammalian cell culture
- Hands-on experience in protein production, preferably from mammalian host cells
- Hands-on experience in protein analytics, including SDS-PAGE, Western blot, and plate based spectroscopic and luminescent assays
- Familiarity with automated Simple Western instruments (Leo, Jess, Abby) is a plus
