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Senior Manager, HEOR & RWE

ArcellxRedwood City, California, United StatesOnsite

Who We Are


Arcellx isa public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible.Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California.

At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work.

What Matters to Us


Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team.Arcellx Core Values

  • Character: Committed to always doing what’s right.
  • Audacity: Willing to challenge convention and share candid feedback with others.
  • Determination: Curious and self-motivated. Always looking to improve and learn.  
  • Collaboration: "No job is too small" mentality. Humble and willing to help others.
  • Originality: Will bring your unique perspective to the table and respect a diverse set of views and backgrounds.

How You’ll Make a Difference


As the Senior Manager, HEOR & RWE, you are responsible for generating evidence to demonstrate the value of anitocabtagene autoleucel (anito-cel), our lead CAR T-cell therapy candidate for the treatment of patients with relapsed refractory multiple Your work in this role will help advance our therapy to market and ensure anito-cel is delivered to multiple myeloma patients in need of more options in their treatment journey.

The “Fine Print” – What You’ll Do 


  • Conduct or support HEOR/RWE initiatives to support and strengthen unmet need or product value demonstration for late pipeline programs, as well as strategic decision making for early clinical development programs.
  • Provide fit-for-purpose HEOR input for clinical trial design, ensuring ability to meet regulatory requirements, address patient priorities, and optimize access opportunities.
  • Apply technical training and experience to plan, execute, and interpret research and data collection activities.
  • Engage with internal and external experts and data resources to execute strategies and research activities led by HEOR/RWE.
  • Implement impactful research dissemination activities to inform internal decision-making and appropriately contribute to external scientific knowledge and literature.
  • Actively participate in cross-functional teams as subject matter expert for tactical discussions and proactively escalate challenges.
  • Monitor scientific, regulatory, reimbursement and access trends. 

Skills and Experience We Look For


  • PhD in Epidemiology, Economics, Econometrics, Health Services Research or related field; or PharmD with completion of 2-year postdoctoral fellowship in outcomes research or related field.
  • Minimum of 2 years of relevant full-time experience in the pharmaceutical industry or related industry. Prior oncology experience a plus.
  • Experience and/or substantial training in the scientific fundamentals of one or more of the core HEOR/RWE specialties.
  • Track record of performing HEOR or RWE projects from inception through publication and application with minimal oversight.
  • Fundamental knowledge of the US regulatory and PR&A landscape, as well as understanding of other development-related functions as they relate to all phases of drug development.
  • Strong capabilities to perform the dual roles of working within a cross functional environment and leading independent scientific research.

Rewards at Arcellx


Our people are our greatest asset, and supporting their well-being is an essential part of delivering on our mission and impacting the lives of patients. Putting this belief into practice means offering strong compensation and benefits.The base salary range for this position is $185,000 - $195,000 per year. Where a candidate falls within that range is determined by factors such as years of experience. Our compensation package also includes an annual bonus based on company goals and an equity (RSU) grant.

We do offer relocation assistance for roles if required.Our market-leading benefits package includes: 100% coverage for medical, dental and vision for team members and dependents, unlimited vacation, a 3-day weekend every month, fully-paid parental leave for up to 6 months, tuition reimbursement, 401k employer contribution and more. 

Join us in our quest to reimagine cell therapy and destroy cancer. For more on our technology, culture, and team, go to


www.arcellx.com


.


 #LI-Onsite

Life at Arcellx

Arcellx is a clinical-stage biopharmaceutical company developing novel, adaptive and controllable cell therapies for the treatment of patients with cancer and autoimmune diseases. The Company's proprietary ARC-sparX platform separates the tumor-recognition and tumor-killing functions of conventional CAR-T cell therapies: (1) sparX (soluble protein antigen-receptor X-linkers) proteins recognize and bind specific antigens on diseased cells and flag those cells for destruction; and (2) ARC-T (Antigen Receptor Complex-T) cells bind the sparX proteins and kill the flagged cells. Arcellx has developed a collection of sparX proteins that bind different cell surface antigens. Administration of alternate sparX proteins can redirect ARC-T cells to different disease antigens to potentially address relapsed and refractory disease due to tumor heterogeneity or antigen escape. Additionally, ARC-T cell activity can be curbed as needed by controlling the dose and frequency of sparX administration.
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